Αξιολόγηση χρονικής διάρκειας επεισοδίων κολπικής μαρμαρυγής στην εκτίμηση κινδύνου για ισχαιμικό ΑΕΕ (Master thesis)

Φέκας, Αθανάσιος

Atrial fibrillation is one of the most frequent arrythmias. Stroke is the major complication of atrial fibrillation. According to the guidelines and the risk scales, the stroke risk is not based on the duration of the atrial fibrillation or the pattern. Treatment with anticoagulants is necessary in most of the patients in order to prevent thromboembolic events. The pattern or the duration of the atrial fibrillation are not included in the guidelines for treatment initiation with anticoagulants. Αims The aim of this review is the evaluation of the clinical significance of the atrial fibrillation duration in the assessment and management of the stroke risk in patients with atrial fibrillation. Methods A systematic search of the Pubmed database was proceeded. Studies in english, evaluating the relation between the duration of atrial fibrillation and the stroke risk and also studies evaluating the relation between different patterns of atrial fibrillation and the stroke risk were included. After an initial assessment of 42 articles, data from 16 articles were included. Results From the findings of the studies that evaluate the relation between the pattern of atrial fibrillation and the stroke risk, there is relation between the atrial fibrillation burden and the stroke risk and since the atrial fibrillation burden is significant, the precise evaluation of the burden is crucial. Studies that used implanted record devices could continuously record , detect and quantificate the atrial fibrillation burden and relate the atrial fibrilation duration with the stroke risk and also provide the specific sub-category of atrial fibrillation patients that will benefit from the anticoagulation treatment. The precise quantity of atrial fibrilation burden that is necessary to increase the stroke risk is not fixed and these studies are suggesting duration of atrial fibrillation with a range from >5 minutes to >24 hours. Conclusion All the studies that assessed the relation between subclinical atrial fibrillation and stroke risk concluded that there is relation between the duration of the atrial fibrillation and the stroke risk. The analysis of these studies indicates that the atrial fibrillation burden correlates with stroke risk, but not as a direct causative factor of stroke.
Institution and School/Department of submitter: Δημοκρίτειο Πανεπιστήμιο Θράκης. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
Subject classification: Cerebrovascular disease
Keywords: Αγγειακό εγκεφαλικό επεισόδιο,AEE,Κολπική μαρμαρυγή,Εμφυτεύσιμες καρδιακές συσκευές,Stroke,Atrial fibrillation,Ιmplantable cardiac devices
URI: https://repo.lib.duth.gr/jspui/handle/123456789/11205
http://dx.doi.org/10.26257/heal.duth.9988
Appears in Collections:Π.Μ.Σ. ΑΓΓΕΙΑΚΑ ΕΓΚΕΦΑΛΙΚΑ ΕΠΕΙΣΟΔΙΑ

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http://dx.doi.org/10.26257/heal.duth.9988
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