Μέθοδοι αξιολόγησης των ωοθηκικών αποθεμάτων (Master thesis)
As a result of social trends many women elect to postpone their first pregnancy to a later stage in life. A large part of this population will be infertile by the time they opt to conceive, mainly because of a decreasing ovarian reserve and low oocyte quality resulting from age. In a subfertile population the availability of an accurate screening test of ovarian reserve would provide a useful means of predicting the chances of pregnancy and live birth with or without treatment and selecting an optimal dose of ovarian stimulation where treatment using ovarian stimulation is necessary. The following hormonal and ultrasound markers ave been used to attempt to estimate ovarian reserve and predict those with a poor chance of success in assisted reproductive techniques: age, concentrations of follicle stimulating hormone - FSH, estradiol, inhibin B, antimullerian hormone - AMH, ovarian antral follicle count - AFC, ovarian volume and ovarian stromal blood flow. There are also dynamic tests like clomiphene citrate challenge test - CCCT, exogenous follicle stimulating hormone ovarian reserve test - EFORT and gonadotropin releasing hormone agonist stimulation test - GAST. The use of a wide range of tests suggests that no single test provides a sufficiently accurate result. Nevertheless, assays like AMH and AFC have proven usefulness as markers of diminished ovarian reserve and predictors of response to ovarian stimulation in patients undergoing in vitro fertilization treatment.
|Institution and School/Department of submitter:||Δημοκρίτειο Πανεπιστήμιο Θράκης. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής|
|Subject classification:||Human reproduction|
|Keywords:||Ωοθηκικά αποθέματα,Ορμονικοί και υπερηχογραφικοί δείκτες,Υπογονιμότητα,Τεχνητή γονιμοποίηση,Ovarian reserve,Hormonal and ultrasound markers,IVF,Fertilization in vitro|
|Appears in Collections:||Π.Μ.Σ. ΑΝΘΡΩΠΙΝΗ ΑΝΑΠΑΡΑΓΩΓΗ|
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|ValsamidisΚ_2016.pdf||Μεταπτυχιακή εργασία||1.33 MB||Adobe PDF||View/Open|
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