Μελέτη τοπογραφικής ανάπλασης του επιθηλίου του κερατοειδή χιτώνα μετά από διαθλαστική χειρουργική (Master thesis)
Καφετζή, Δέσποινα
In recent years there has been an increased interest in refractive surgery, as patients with refractive errors more easily become subjected to a procedure that can facilitate their lives. An important role for this is attributed in the development of imaging technology, and particularly that of the cornea, which ensures premium refractive effect with accuracy, and facilitates improvements in recovery time and quality of life. Cornea is the tissue that is subjected to the intervention, and therefore each layer is thoroughly studied with topographical maps. In recent years there is scientific interest in corneal epithelium because it is the first anatomic layer and thus becomes more challenged in refractive surgery. PURPOSE
We studied corneal epithelial thickness before and after refractive surgery, in order to analyze the changes that are developed after the operation.MATERIALS AND METHOD. We studied and recorded the changes that occurred in the cornea after trans-PRK using Anterior Segment Optical Coherence Tomography (AS OCT). The study included 30 eyes of patients, after having signed the relevant informed consent document, they were subjected to measurements as they were defined by the study protocol. Accordingly, we measured the thickness of the cornea and corneal epithelium pre-operatively and at three and six months postoperatively with A-S OCT. Specifically, we studied the thickness of the central cornea (Central Corneal Thickness), at a radius of 3 mm and a radius of 5 mm, and the thickness of the epithelium (Epithelial Thickness) centrally, at a radius of 3 mm and a radius of 5 mm.
All patients were divided into subgroups according to sex, age and degree of the refractive error. The analysis was performed in each subgroup preoperatively and at three and six months post-operatively. RESULTS. Parameters were subjected to analysis (corneal thickness and epithelial thickness), did not show a statistically significant difference between the measurements at three and six months post-operatively. Thus it seemed that the healing process of the corneal epithelium is completed in three months after refractive surgery with trans PRK. As the statistical analysis indicates, there is a possibility on some of these subgroups, such as the thickness of the cornea and epithelium in older age groups for example, if the statistical sample becomes bigger, perhaps a statistically significant difference will be unmasked for that group of patients.DISCUSSION. For this study, we employed a Spectral Domain AS-OCT, the Heidelberg (Heidelberg Engineering GmbH, Heidelberg, Lubeck, Germany), which provides fast and reliable analysis, and has not been studied much in the literature for the measurement of the corneal thickness and epithelium. The reliability of Heidelberg makes us wonder if beyond the quantitative aspect, i.e. the final visual acuity and achievement of emmetropia, should there be a concern for the maintenance of the therapeutic effect over time in older patients, which may lead to more intense monitoring for these patients. Certainly, studies with larger numbers of patients are needed to draw firm conclusions.
Alternative title / Subtitle: | μελέτη με Οπτική Τομογραφία Συνοχής προσθίου ημιμορίου |
Institution and School/Department of submitter: | Δημοκρίτειο Πανεπιστήμιο Θράκης. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής |
Subject classification: | Cornea |
Keywords: | Optical coherence tomography,Epithelium,Cornea,Οπτική τομογραφία συνοχής,Επιθήλιο,Κερατοειδής |
URI: | https://repo.lib.duth.gr/jspui/handle/123456789/11810 http://dx.doi.org/10.26257/heal.duth.10592 |
Appears in Collections: | Π.Μ.Σ. ΙΑΤΡΙΚΗ ΑΠΕΙΚΟΝΙΣΗ ΣΤΗΝ ΟΦΘΑΛΜΟΛΟΓΙΑ |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
KafetziD_2017.pdf | Μεταπτυχιακή εργασία | 4.82 MB | Adobe PDF | View/Open |
Please use this identifier to cite or link to this item:
This item is a favorite for 0 people.
https://repo.lib.duth.gr/jspui/handle/123456789/11810
http://dx.doi.org/10.26257/heal.duth.10592
This item is licensed under a Creative Commons License