Γλαύκωμα σε μυωπικούς ασθενείς διαγνωστική αξία SD-OCT Posterior Pole Asymmetry Analysis (PPAA) και RNFL thickness (Master thesis)
Ντακοβάνου, Βασιλική
Glaucoma represents a group of diseases characterized by optic neuropathy. The modern view is that glaucoma is a multifactorial disease. Whatever the rationale mechanism is, retinal ganglion cell axons lead to apoptosis, and this damage extends from the optic disc to the brain's visual centers, causing characteristic visual field defects. We use the term preperimetric glaucoma to define those cases that have begun to cause lesions in the optic nerve without yet being visible in the patient's visual field and therefore not perceived by him. In these cases it is now possible to detect them using Optical coherence tomography and in particular the method of measuring thickness of peripapillary retinal nerve fibers, contributing to the early diagnosis and prevention of glaucoma. In the case of myopic patients, their anatomical variations (tilting, torsion, thinning of peripapillary nerve fiber layer) question the reliability of measuring the thickness of peripapillary retinal nerve fibers as a method for early diagnosis. In the context of investigating an alternative method for early diagnosis of glaucoma in myopia, we tested the method of measuring posterior pole retinal thickness and asymmetry of thickness between hemispheres, factors that are not affected by the anatomical features of myopia. Recent research indicates that the mid-circumference of posterior pole may not be taken into account, and suggests that posterior pole is divided into zones, of which only the central (zone 3) is reliable in estimating asymmetry. The following study examined the diagnostic value of posterior pole retinal thickness and posterior pole (central zone) asymmetry analysis in the diagnosis of glaucoma in myopic patients and compared it with the diagnostic value of peripapillary retinal nerve fiber layers’ thickness. All three methods have proven to be reliable and useful tools in the clinical diagnosis of preperimetric glaucoma in myopic patients but posterior pole central zone asymmetry analysis seems to be the most accurate.
Institution and School/Department of submitter: | Δημοκρίτειο Πανεπιστήμιο Θράκης. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής |
Subject classification: | Glaucoma |
Keywords: | Glaucoma,Myopia,Optical coherence tomography,Γλαύκωμα,Μυωπία,Οπτική τομογραφία συνοχής |
URI: | https://repo.lib.duth.gr/jspui/handle/123456789/11900 http://dx.doi.org/10.26257/heal.duth.10682 |
Appears in Collections: | Π.Μ.Σ. ΙΑΤΡΙΚΗ ΑΠΕΙΚΟΝΙΣΗ ΣΤΗΝ ΟΦΘΑΛΜΟΛΟΓΙΑ |
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File | Description | Size | Format | |
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NtakovanouV_2020.pdf | Μεταπτυχιακή εργασία | 2.45 MB | Adobe PDF | View/Open |
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https://repo.lib.duth.gr/jspui/handle/123456789/11900
http://dx.doi.org/10.26257/heal.duth.10682
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