Repository of DUTH

Ο επιπολασμός της επιωχρικής μεμβράνης όπως καταγράφηκε με τη βοήθεια της Τομογραφίας Οπτικής συνοχής (SD-OCT) στον πληθυσμό του Thessaloniki Eye Study (Master thesis)

Σταμούλας, Κωνσταντίνος

Purpose: To estimate the prevalence of epiretinal membrane and vitreoretinal surface abnormalities as measured by spectral-domain optical coherence tomography (SD-OCT) in an elderly population of Thessaloniki and to describe risk factors associated with epiretinal membrane. Design: Cross-sectional, population-based study. Participants: There were 1092 participants aged 74 to 101 years at the 12-year Thessaloniki Eye Study (TES) follow-up examination in 2013-2015, of whom 862 had gradable spectral-domain optical coherence tomography scans of the macula in at least one eye. Methods: The presence of epiretinal membranes and other vitreoretinal surface abnormalities was determined by standardized grading of macular SD-OCT scans. Main Outcome Measures: Epiretinal membranes (ERMs), vitreomacular adhesion (VMA), vitreomacular traction (VMT), lamellar holes (LHs), full=thickness macular holes (FTMHs) and intraretinal cysts (IRCs). Results: By using SD-OCT, the prevalence of epiretinal membranes (54,8%), vitreomacular adhesion (19,4%), vitreomacular traction (2%), lamellar holes (2,3%), full-thickness macular holes (0,5%) and intraretinal cysts (5,9%) was determined. The prevalence of epiretinal membranes was 51,2%, in participants 74 to 78 years of age, 54,1% in participants 79 to 83 years of age and 65,5% in participants 83 years of age and older. Signs of ERM were bilateral in 46,8%, VMA in 35,9%, VMT in 17,6% and IRCs in 15,7%. LHs and FTMHs were found only unilaterally. The prevalence of secondary ERMs was higher than that of idiopathic ERMs. Overall center-involving ERMs were more common in men (9,3%) compared with women (4,6%). Secondary ERMs affecting the fovea were also more frequent in men (13,5% versus 6,9%). Age, age-related macular degeneration and laser photocoagulation (focal or panretinal) were significantly associated with ERMs. Conclusion: This study has documented the frequency of epiretinal membranes and other retinal lesions in an older population. Risk factors associated with ERMs were increasing age, age-related macular degeneration and laser photocoagulation.