Φυλογενετικά σενάρια σε βαλκανικούς πληθυσμούς (Bachelor thesis)

Χατζηπανώριας, Γεώργιος

The Balkan Peninsula area has a big variety of populations that belong to different nationalities with different cultural backgrounds. In this study, 212 individuals were collected and examined on the differences of their genetic material. Those individuals belong to one of the following populations: Bosnia, Bulgaria, Croatia, Italy, Kosovo, Northern Macedonia, Montenegro, Serbia, Slovakia, Slovenia, Greece, Ukraine and Moldavia. The purpose of the present study is to analyze the genetic material of these populations in order to explore their differences on genetic level. The differences that are observed on their genepool, have emerged thanks to all the factors that contribute to genetic diversity. This work employed freely available genetic data to study, the population structure of the Balkans, as well as to formulate different scenarios for the migration path followed by the ancestors of each population. In the analysis we used bioinformatic tools that include statistical and algebraic models (such as principal component analysis) and a combination of different programming languages (Python, R, Bash) to formulate possible scenarios for the migrations that took place in the past and formed all the modern populations in the geographical area of the Balkans. The results of our research indicate that there are significant differences between the populations of the North and the South, and to a lesser extent differences between East and West.
Institution and School/Department of submitter: Δημοκρίτειο Πανεπιστήμιο Θράκης. Σχολή Επιστημών Υγείας. Τμήμα Μοριακής Βιολογίας και Γενετικής
Subject classification: Population Genetics
Keywords: Population genetics,Variant,Balkans,Γενετική πληθυσμών,Βαλκάνια,Πολυμορφισμοί
URI: https://repo.lib.duth.gr/jspui/handle/123456789/17214
http://dx.doi.org/10.26257/heal.duth.15948
Appears in Collections:ΤΜΗΜΑ ΜΟΡΙΑΚΗΣ ΒΙΟΛΟΓΙΑΣ & ΓΕΝΕΤΙΚΗΣ

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https://repo.lib.duth.gr/jspui/handle/123456789/17214
http://dx.doi.org/10.26257/heal.duth.15948
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